FURI Current Student Research

 

Highlighting Victoria Smith & Anngela Adams’s FURI research mentored by Jeffrey LaBelle as featured on the Arizona State University’s FURI research website.

 

Characterizing the antibody of Estradiol

Victoria Smith, Spring 2014

Mentor: Jeffrey LaBelle, assistant professor

The proposal and goal of this research is to characterize the antibody of the hormone Estradiol, an estrogen hormone, in order to detect its concentration in the blood during the menstrual cycle. Over six million women in the United States struggle with becoming or staying pregnant. Many women who experience difficulties in becoming pregnant turn to fertility treatments like ovulation stimulation. One of the main reasons it is difficult for some couples to conceive is their inability to accurately predict the ovulation period. It is during this small window of ovulation that couples have the greatest opportunity of becoming pregnant.

Ovulation is a response to different hormone concentrations in the blood and occurs at regular intervals; however, these intervals are different for every woman. By mapping out the concentrations of the central hormones – estrogen, progesterone, human chorionic gonadotropin – an accurate timeline can be produced and analyzed. The analyzed data would provide information on the optimal time of ovulation for each individual woman.

The main focus of this project is to characterize the hormone Estradiol using electrochemical impedance spectroscopy for the development of a fertility sensor. …

TOUCH tear glucose-sensing testing

Anngela Adams, Spring 2014

Mentor: Jeffrey LaBelle, assistant professor

My research is focused on making crucial improvements to the current TOUCH tear glucose-sensing device, which provides a non-invasive method of monitoring blood glucose using tear fluid instead of blood. The biosensor is at a critical stage of its development.

Currently the device uses liquid reagents that must be pumped into microfluidic, which makes tear sample collection difficult and shelf life too short to be commercially viable. In order to reach the market and help millions of diabetics, the tear glucose sensor needs to improve ease of sampling and shelf life. …

My research is to develop a new device that uses capillary action in microfluidic with dry reagents, in order to improve the usability and marketability of the sensor. …

This semester’s research has been very productive and successful. I really appreciate this opportunity. This is my last semester in FURI and I have really enjoyed it. My favorite part of FURI this semester was at the poster symposium when I got to present my research to Dr. Fulton!

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